Orbexa®
Eurand's Orbexa® technology is a multiparticulate system that enables high drug loading and provides a formulation choice for products that require granulation.
How it Works
This technology produces beads that are of controlled size and density using granulation, spheronization and extrusion techniques. The process involves the extrusion of a concentrated formulation of a drug through a fine nozzle. The extruded drug is then cut and shaped, in a spheronization process, to produce beads suitable for formulation as controlled release multiparticulates. The resultant beads can be coated with functional polymer membranes for additional release rate control and may be filled into capsules or provided in sachet form.
This process allows for high drug concentrations within each bead. The technology involves high speed processes making it suited for use with sensitive drugs such as proteins.
Eurand's Orbexa technology can be used for:
- Gastroprotection of drugs
- Delayed or enteric release
- Sustained release
- Targeted delivery
- Pulsatile delivery
- Separation of chemically incompatibles ingredients
- Combination products
For more information on this technology, please contact us at partners@eurand.com